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Jake goes in for his check up and shots on Saturday- He's been on Temaril- P for allergies- which has prednisone in it-for a couple of months- He is on just a tiny amount because I weaned him down as quick as I could- He gets 1/2 tab every 2-3 days- but if I try to let it go longer he starts scratching and sneezing- My concern is is it safe to give vaccine when they have been on prednisone? I called the vets office and he said it was perfectly fine (and I do trust him) but I'm always nervous around shot time- The funny part is- parents have the same concerns giving vaccines to babies- and I never hesistate to encourage them to get the baby shots - I'm such a wuss!!