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I have heard from a couple of vets that vaccinations can exacerbate allergies. I had one older dog with severe allergies, his vet said in no uncertain terms "No more shots!".

I am not anti-vaccination, but I don't believe that they need to be done annually, I do my hounds every three years. They do still need their annual check-up.

Do you know what he is allergic to? Have you tried playing around with his diet? Nutrition can often make a BIG difference with allergies, but it takes a fair amount of experimentation to find out what works for a particular dog.
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