Basset Hounds Forum banner

Vaccines--Duration of Immunity Challenge Study

4026 Views 19 Replies 7 Participants Last post by  biscuit
This abstract from PubMed

Vet Ther. 2004 Fall;5(3):173-86.

Evaluation of the efficacy and duration of immunity of a canine combination vaccine against virulent parvovirus, infectious canine hepatitis virus, and distemper virus experimental challenges.

Abdelmagid OY, Larson L, Payne L, Tubbs A, Wasmoen T, Schultz R.

Schering-Plough Animal Health, Research and Development, 21401 West Center Road, Elkhorn, NE, USA.

The results obtained from this study confirmed that dogs vaccinated subcutaneously with a commercially available multivalent vaccine containing modified-live Canine Distemper Virus (CDV), Canine Adenovirus Type 2 (CAV-2), Canine Parvovirus Type 2b (CPV-2b) and Canine Parainfluenza Virus (CPI) antigens were protected against sequential experimental challenge by virulent canine parvovirus type 2b, infectious canine hepatitis virus, and canine distemper virus administered 55-57 month after initial vaccination given at 7-8 weeks of age. All 10 vaccinates (100%) were protected against clinical diseases and mortality following parvovirus and infectious canine hepatitis experimental infections. All vaccinates (100%) were protected against mortality and (90%) were protected against clinical disease following distemper challenge. Therefore, the data obtained from this study supports at least 4 year duration of immunity for these three "core" fractions in the combination vaccine.
1 - 1 of 20 Posts
Jean Dodds used to be very well respected within the veterinary medical community-it's my understanding that may have changed.

I have a number of concerns about this new protocol even though Roady gets his vaccinations every 3 years, except for bordatella which he gets yearly. First I agree with Betsy about wanting to see more long term studies. Secondly I'm concerned about sky-rocketing veterinary costs. Vaccinations, Heartworm and Flea Products are where vets make their money. Without vaccinations we're going to be making up the difference elsewhere. My vet told me once what her costs were for surgical procedures, like a spay or lumpectomy. After paying for the anesthetic, the tech and her salary, there's really not a hec of a lot of profit. What I pay for Roady's lab tests and x-rays is really cheap compared to human medicine. I think the average salary for a veterinarian was $45,000 last time I looked it up.

I'm not saying we should stick with yearly vaccinations if studies prove a 3-year protocol is better long term but I think we should also be prepared to pay more for higher priced items.

Another question I had was why so many pet shop and BYB dogs come down with parvo and distemper? If this life long immunity after the initial vaccination is true than they must not be vaccinating at all. Or maybe the dogs have become infected prior to the initial vaccination.

Just a few thoughts on this subject......
See less See more
1 - 1 of 20 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.