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pano is self regulating in that over time once the dog stops growing it resolves itself. The pain can be intense for the dog If the dog lost 8lbs inorder to loss that much weight that quickly a large portion has to be fluids. I would be worryied about dehydration even with sub Q's. Never had a problem with mine eat with pano. I would not be surprised if the cause of the not eating is still not gastrointestinal related. If he drinks but does not eat you can try substituting low sodium, chicken stock for water.
FWIW pano ussually begins in the front end given you said knee I am assuming he is limping on a back leg.
FWIW pano ussually begins in the front end given you said knee I am assuming he is limping on a back leg.