“Melamine at high doses causes a pronounced diuretic affect in dogs and rats, as well as the development of crystals in their urine,” said Dr. Steven Hansen, veterinary toxicologist and senior vice president with the ASPCA, who manages the ASPCA’s Midwest Office, including its Animal Poison Control Center (APCC). “The twist in the tale is that melamine itself has a very high safety margin, especially when compared with a toxin such as aminopterin.
“Cats, however, are a very sensitive species, and can react adversely to many chemicals and drugs,” continued Dr. Hansen. “Because of their unique physiology, we suspect that they may also be more sensitive to the adverse effects of melamine.
“Further, crystals in urine have been reported by veterinary diagnosticians and clinicians in some of the pets affected by the contaminated foods. However, the direct connection between melamine and renal failure, especially in cats, is not clear and requires additional investigation.”
The ASPCA recommends that the treatment of pets for kidney failure, which has been directly linked to ingestion of the contaminated food, should continue. “It is imperative to stay in close contact with your veterinarian and follow their direction,” said Dr. Hansen. “In addition, if you have any suspicion that your pet is displaying signs other than those previously noted, and believe these are directly linked to ingestion of the contaminated food, you should notify the FDA immediately.”[/b]
