[Betsy Iole]

While the very purpose of testing the liver enzymes is early recognition of problems to provide opportunities for earlier and more meaningful intervention, the veterinary practitioner is challenged to determine if the abnormal result really does constitute a problem. Veterinary internists are often asked to consult about middle aged to older dogs that have moderately elevated serum levels of alkaline phosphatase (ALK, ALP, SAP), a commonly measured liver enzyme.

If pets appear otherwise well, it is exceedingly important to verify the abnormal result before pursuing it as a potential problem. In other words, the veterinarian will need to make sure that the abnormality shows up on re-tests and not just a fluke. Repeating the lab test in one to two weeks with ideal patient preparation is common. Once the abnormality is verified, the veterinarian can try to determine whether the patient’s health is in danger.

Full article is here: When "Normal" Dogs Have Abnormal Liver Enzymes.

 

[Betsy Iole]

The only liver condition reported in BHCA's Health Survey (1998) was portosystemic shunt. This condition is known to be hereditary in some breeds, including Irish Wolfhounds and Maltese, and maybe in some other terriers. In this condition, abnormal blood vessel connections shunt blood from the intestines around the liver, instead of through the liver. Because the blood doesn't go through the liver, harmful substances aren't metabolized by the liver, and these substances build up to toxic levels in the circulation. See also What is a portsystemic shunt?.

I'm also aware of isolated reports of chronic hepatitis in Bassets. This isn't a single condition; it may have many causes and isn't well characterized in dogs.

 

[Betsy Iole]

Another discussion of liver tests.

Diagnosing Liver Disease in Dogs: What do the Tests Really Mean?

And...

Structure and Function of the Liver

[ February 21, 2004, 03:30 PM: Message edited by: Betsy Iole ]