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I'll be curious how the shots go. Pearl's been on them for three months, and I don't think I see an effect yet. They said it could take up to a year, and that they'll work for about 70% of the dog. What really seems to be helping is--of all things--an air filter in the room she sleeps in. She's allergic to a bit of everything--cat dander, grass, trees. Hope the shots work for both Louie and Pearl.