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No answers for you, but a couple of thoughts.

How old is Arlo? Was he fully house-trained before the surgery?

How did you treat him when he came home from the surgery? Did you make a big fuss over him? Did you make a point of staying with him when he went out for a pee? After supper what's your family routine? Does everyone go off and do something? Perhaps after the hustle and bustle of getting dinner ready, he feels lonely. Perhaps he's afraid of the dark.

I would try taking him out on a leash. If he hesitates at the door, bribe him out with a treat and reward him when he does what he's supposed to do. All-in-all, make it a positive experience for him.

I'm with you about giving drugs (to me or my babies) unless I understand why.

Good luck.
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